In the present work we have synthesized benzothiazole with dithiocabamate side chain substituting different alkyl/aralkyl halides and calculated molecular properties by mol inspiration, Osiris, molsoft software’s and ALOPGPS 2.1 program. Structures of the new compounds were established by 1HNMR, IR, Mass spectral data and elemental analysis. All of the synthesized compounds (4a-4g) obey lipinski’s “rule of five” and other parameters. The newly synthesized compounds were evaluated for antibacterial and antifungal activities. The final synthesized compounds have exhibited promising antibacterial antifungal activity.
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